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Jawaharlal Nehru Technological University Hyderabad
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| Kukatpally, Hyderabad - 500 085, Andhra Pradesh, India |
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M. Laxmi Narasu M.Sc.,Ph.D
Director,
Institute of science and Technology |
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Educational Qualifications
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Ph. D. Microbiology from Indian Institute of Science Bangalore in1987 |
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M. Sc. Microbiology from Osmania University, Hyderabad in 1979 |
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Title of Doctoral Thesis Studies on larvicidal protein from Bacillus sphaericus in 1993 |
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Research & Teaching Profile
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Research experience 28 years |
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Teaching experience 19 years |
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TEQIP Coordinator(World Bank Project) 2004-2008 |
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Total no. of Ph.D students guided- 12 |
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Research projects completed- 8 |
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On going research projects- 1 |
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Total no of publications in peer reviewed journals- 50 |
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Patents 1 patent filed |
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Research Interests
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Works in the areas of Industrial enzymes, Protein purification, Bioconversions and Cancer Research |
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Achievements
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Awarded AICTE career award for young teachers in the year 1996 for the proposed work on transformed root cultures of Artemisia annua. |
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Membership in Professional Bodies
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Fellow of Biotechnological and Pharmacy, India |
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Life Member, Indian Society for Analytical Chemists |
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Life Member, Society for Biological Chemists, India |
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Life Member, Indian Science Congress Association |
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Life Member, Association of Microbiologists, India |
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List of most recent Publications
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Archana Giri, C.C.Giri, Vikas Dhingra and Lakshmi Narasu.M (2001) Enhanced Podophyllotoxin Production from Agrobacterium rhizogenes transformed cultures of Podophyllum hexandrum Natural Product Letters 15 (4), 229-235 |
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Rao.K.K.. Lakshmi Narasu.M., and Jena,K.K. (2002) DNA markers and marker-assisted breeding for durable resistance to bacterial blight disease in rice., Biotechnology Advances 20 (1),33-47 |
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Udayshankar.A and Lakshmi Narasu.M., (2002) Association between the 102 T/C polymorphism of Serotonin –2A Receptor gene and Schizophrenia among South Indians, Molecular Psychiatry 7 (6), 540-541. |
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Rao.K.K. Lakshmi Narasu.M., and Jena,K.K. (2002) “Molecular tagging of a new bacterial blight resistance gene in rice using RAPD and SSR markers”, Plant Breeding 28 (1),16-17. |
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Bharathi, Kodali., Bhagavanth Rao., Lakshmi Narasu, M., Ravindra Pogaku. (2004) “Effect of biochemical reactions in enhancement of rate of leaching”, Chemical engineering Science, 59, 5069-5073. (2004) |
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V. Girijashankar¹_², H. C. Sharma¹, Kiran K. Sharma¹, V. Swathisree², L. Sivarama Prasad¹,B.V.Bhat¹, Monique Royer³, Blanca San Secundo 4 , M. Lakshmi Narasu², I. Altosaar 5, and*N. Seetharama¹.”Development of Transgenic Sorghum for Insect Resistance against the Spotted Stem Borer (Chilo partellus)”Plant cell reports. (2005) |
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Radhika Tatineni, Kiran Kumar Doddapaneni, Ravi Chandra Potumarthi, Lakshmi Narasu Mangamoori, (2006) “Optimization of keratinase production and enzyme activity using response surface methodology with Streptomyces sp7.” Accepted for publication in Applied Biochemistry and Biotechnology. |
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Radhika Tatineni, Kiran Kumar Doddapaneni, Sailasree Dalavayi, Santosh Kulkarni, Lakshmi Narasu Mangamoori, (2006) “Microbacterium trichotecenolyticum enzyme mediated transformation of arteannuin B to artemisinin.” Accepted for publication in Process Biochemistry. |
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Vellanki R.N., Komaravelli N., Gupta P., Choudhary M.L., Narasu M.L., Khatri G.S. (2006). Constitutive expression and characterization of Hepatitis B surface antigen purified by metal affinity precipitation. Biotechnol. Appl. Biochem. (in Press) doi:10.1042/BA20060008. |
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Komaravelli N., Gupta P., Vellanki R.N., Choudhary M.L., Narasu M.L. and Khatri G.S (2006). Immunization of mice with Autolysin - Adhesin (Aaa) provides protection against Staphylococcus aureus and Staphylococcus epidermidis infection. Clinical Immunology. doi 10.1016/j.clim.2006.05.013. |
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Vellanki R.N., Komaravelli N., Gupta P., Choudhary M.L., Narasu M.L. and Khatri G.S. (2006). Constitutive intracellular expression and characterization of recombinant streptokinase in Pichia pastoris expression system. Prot. Expr. Purif. (in Press) doi: 10.1016/j.pep.2006. |
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Cherukuri Sudhakar and Lakshmi N Mangamoori, Significance of glycosylation patterns of rat Zajdela ascitic hepatocellular carcinoma: Effect of enzymatic removal of surface sialic acid on humoral response, accepted publication in Journal of Gastroenterology and Hepatology, doi: 10.1111/j.1440-1746.(2007) |
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Kiran Kumar Doddapaneni, Radhika Tatineni, Ravi Nagaraj Vellanki, Bharat Gandu, Nagender Reddy Panyala, Balumaddileti Chakali, Lakshmi Narasu Mangamoori “Purification and characterization of two novel extra cellular proteases from Serratia rubidaea” accepted for publication on 22 May 2007 in Process Biochemistry, doi:10.1016/j.procbio.(2007). |
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Kiran Kumar Doddapaneni, Radhika Tatineni, Ravi Nagaraj Vellanki, Sangeetha Rachcha, Naveen Anabrolu, Venkanna Narakuti, Lakshmi Narasu Mangamoori “Purification and characterization of a solvent and detergent-stable novel protease from Bacillus cereus” accepted for publication 10 April 2007 in Microbiological Research, doi:10.1016/j.micres. (2007). |
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Venkanna Narkuti, Ravi N Vellanki, Gandhi Kpc; Kiran K Doddapaneni; Pramila D Y; Lakshmi narasu Mangamoori, (2007) “Microsatellite mutation in the maternally/paternally transmitted D18S51 locus: Two cases of allele mismatch in the child”. Accepted for publication in Clinica Chimica Acta. (2007) |
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D.Srivaramakrishna, D. Sreekanth, V. Himabindu, M. Lakshmi Narasu and Y. Anjaneyulu, Effect of Thermophillic temperature on biohyrogen production from rice brawn de-oiled waste water by selevtively enriched slaughterhouse sludge, accepted publication in International Journal of Hydrogen Energy,( 2008). |
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No. of Projects Completed /Ongoing as Chief Coordinator/Co-Investigator
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Name of the funding agency (AICTE/Others) |
Name of the Scheme |
Programme Title |
Year of Funding |
Duration |
Amount sanctioned |
Status completed / Ongoing |
| 1 |
MHrd |
R & D |
Application of Plant tissue culture systems for crop improvement |
1993 |
3 years |
6 lakhs |
Completed |
| 2 |
AICTE |
R & D |
Tissue culture of Artemisia annua.) |
1996 |
3 years |
3 lakhs |
Completed |
| 3 |
AICTE |
R & D |
Transformed Cultures of Artemisia annua) |
1995 |
2 years |
2 lakhs |
Completed |
| 4 |
DST |
R & D |
Studies on bioconversion of arteannuin B to artemisinin) |
1998 |
3 years |
12.78 lakhs |
Completed |
| 5 |
AICTE |
TAPTEC |
Bioaugmented fixed and fluidized Bed reactor for treating high strength effluents |
2000 |
3 years |
9 lakhs |
Completed |
| 6 |
UGC |
R & D |
Studies on microbial Bioconversion of arteannuin B to artemisinin) |
2003 |
3 years |
5.06 lakhs |
Completed |
| 7 |
World Bank |
World Bank assistance |
World Bank funded Programme entitled Technical Education Quality Improvement Programme (TEQIP) for the entire Institute |
Up to Dec 2008 |
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128 Millions rupees. |
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| 8 |
MNRE |
R & D |
Design and development of biological hydrogen production reactors from renewable organic wastes)Collaborative project with Dr.V.HimaBindu of CEN |
2007 |
2 years |
19.52 lakhs |
Ongoing |
| 9 |
Vivimed laboratories (INDUSTRY PROJECT) |
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Microbial Bioconversion route for synthesis of sodium ascorbyl phosphate |
Dec. 2007 |
4 months |
1.35lakhs |
Completed |
| 10 |
Swen genetech (INDUSTRY PROJECT) |
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Purification of lipoprotein lipase |
July2008 |
6 months |
2.00lakhs |
Ongoing |
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| Contact: |
Director,
Telefax : 040-23156128
Res : 040-27891230
Cell: 9490173899
Email:mangamoori@jntuh.ac.in |
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